Eliahu Hanavi Cello Variations by Michael Shapiro

The attached graph is a a model of my facebook network – the cluster at the bottom are work colleagues and at the top are non-work-related social network.

In the middle is my wife!

Yesterday it was once again asserted that a clinical trial comparing TACE to SIRT for eatment of HCC was too hard becuase the sample size would be too large. It was estimated that 1000 to 5000 patients would be required. At the same time it was implied that SIRT was ready for routine use on the basis of the numbers treated already. If such large numbers are needed it is hard to assert that the company and the KOLs truly believe that SIRT is significantly more effective – the larger the effect size the smaller the sample size. 5000 patients might represent the sample size for an equivalence trial. If so then I guess we are asked to assume equivalence to TACE without the trial – and yet there is equipoise.

String Quartet by Jens-Peter Osterndorf played by the Parnasso Quartet on ECM New Series

Gideon Klein Kvartet Op.2

Viktor Ullmann String Quartet No.3 Op.46 composed in Theresienstadt concentration camp

Erwin Schulhoff String Quartet No.1

Heinrich Kaminski String Quartet in F major

Darius Milhaud String Quartet No.2

So for Father’s Day I made my own bacon following an adapted recipe from the Ruhlman book on Charcuterie. You’ll find several versions on the web.

Tasted great if slightly too salty for the end bits. May need to experiment with smoking. Certainly I’ve got enough left to make a tonne of lardons.

The immediately obvious difference compared to regular bacon is that when fried the bacon didn’t release half its’ weight in brine.